as you dont mind...some more non-med-mind 'spanner questions/ramblings'
I can see your meter being v helpful indeed with 'quantifying hypermobility' and it would be totally fab to have a machine to simply and clearly 'medically prove' a collagen defect!
but aren't there lots of different types of poss defect and in the case of HMS and HEDS the exact defect isnt known yet???? and wouldnt you first need to know what exactly the defect is before you can measure it?
and I cant quite see how this 'meter' would 'quantify and qualify' the syndrome, particularly all its non musculo sceletal probs?
as far as I'm aware there's no direct co-relation between 'amount and extent' of hypermobility and 'amount and extent' of syndrome/probs... i.e. there's peops with a 9/9 beighton score that are fine and healthy and peops with a 5/9 that are disabled by chronic non injury pain, autonomic dysfunction etc., (yet dont necessarily suffer the mechanical probs of dislocations).
also I feel there is no difference in my actual hypermobility pre/post becoming 'syndromed'.
well, my right knee has become laxer over the years, but imo that is down to years of overextending, end of range usage...
and as usage of joints and muscle condition have a def influence on mechanical dis/ability... this alone would throw a spanner into 'quantifying/qualifying' probs just by ratio of right/wrong collagen...no?????
so I also cant see how the right/wrong collagen ratio could help "tailor your activities so you can maximise your quality of living without aggravating your pain."
unless the meter could help find that chronic n i pain/autonomic dysfunction are due to minute, not outwardly measurable/seeable increase of wrong collagen... but that would be difficult as peops would have to have had collagen measured BEFORE becoming syndromed...
and sorry but I cant refrain from once again mentioning my simple mind theory (which I feel was somehow strengthened by prof bird's 'hormonal/gynae probs prediction theory') that a lot of the syndrome's probs are not due to hypermobility/wrong collagen per se, but that hm/w c makes us more susceptible to some other 'culprit/mechanism' or 'culpritS/mechanismS' that make the syndrome....
but I could def see how 'meter' could help 'just hypermobile not syndromed' peops try to avoid mechanical damage by tailoring activities...
but like in my case of the syndrome where the main disabling factors are the chronic n i not understood pain and autonomic dysfunction...