Thanks my love, that's very reassuring! I asked my GP before we started trying, and then again when we did start trying just to be on the safe side... She said "amitriptyline's been around for ages, and you're on a low dose, so there's no way that will cause a problem. I think you'll need to review the opioids though, as soon as you know you're pregnant, but not until then" or words to that effect. However, I also spoke to a different GP a couple of years ago who said I should come of absolutely all medication before trying for a baby. Hmmm. When you look at the PIL inside the packet, almost the first thing it says is not to take it if you are pregnant, planning a pregnancy or breast feeding without consulting a doctor. The in the side effects section, it lists some things that sound decidedly endocrine in origin. A poke around the net revealed that amitriptyline can stimulate the production of prolactin from the pituitary, the prolactin in turn suppresses progesterone in the second half of the cycle (and here's where I make a bit of a leap of imagination)leading to hypofertility. Whether it can have this sort of effect with the lowish dose I'm taking, who knows? I think it's just that when you've been trying for a baby for a while and nothing's happening, you start to obsess about what's causing the problem to be honest. I'm going to go back to my GP (who will probably think I'm bonkers), because I don't think I'll rest easy until I've tried coming off amitriptyline for a bit just to see if it helps.
That's the trouble with being a scientist really. A little bit of knowledge and I'm off theorizing, and I don't trust anything until proven empirically
My poor GP...
anyone follow my example! I'd hate to think anyone had changed their meds on the basis of this, when frankly, it's probably a load of rubbish! I'll let you know what my GP and the pharmacist say, and what happens next though.